A national study published by CMA member Aine Clements, MD, exploring whether molecular classification can predict outcomes in endometrial cancer patients continues to gain attention. 

Dr. Clements, who is a PLA alumni and active member of the CMA Women in Medicine community, is a women’s health physician specializing in gynecological oncology at OhioHealth. She was the lead researcher in the study that was published in Gynecology Oncology last year. It garnered so much interest that it was the second-most-cited paper for the journal in 2025. 

Endometrial cancer is the most common gynecologic cancer and is one of the only cancers with an increasing incidence and increasing mortality.  

This means that understanding this disease is crucial. To personalize treatment, we need to understand the differences between cancers. These differences allow us to use weaknesses in cancer growth patterns to use treatments, such as radiation, chemotherapy, or immunotherapy to target cancer cells. This study suggests that patients with certain tumors may benefit from the addition of radiation to chemotherapy. 

"This exciting result is playing an important role in the design of future studies at a national level, and I am so happy to have been able to participate in this work," said Dr. Clements. 

Read the abstract here. 

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